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A recessive mutation to the keratin gene KRT71 is responsible for the growth of a curly rather than straight coat in certain dogs.
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Spezifikationen
| Breeds | Spanischer Wasserhund, Bichon Frise, Chesapeake Bay Retriever, Curly-coated retriever, Irish Terrier, Lagotto Romagnolo |
|---|---|
| Gene | |
| Organ | |
| specimen | Tupfer, EDTA Blut, Heparin Blut, Sperma, Gewebe |
| Mode of Inheritance | |
| Chromosome | |
| Year Published |
Allgemeine Informationen
A recessive mutation to the keratin gene KRT71 is responsible for the growth of a curly rather than straight coat in certain dogs. The variant analysed in this test, designated as c^2, is found in breeds such as the Bichon Frise, Chesapeake Bay Retriever, Curly Coated Retriever and Lagotto Romagnolo. A closely related variant, designated as c^1, is found in the Portuguese Water Dog.
Klinische Merkmale
Affected dogs will have curly instead of straight hairs.
Zusätzliche Information
Es gibt einige Hinweise darauf, dass die Variante möglicherweise einen genetischen Risikofaktor für einige Formen der Follikeldysplasie bei Hunden darstellt.
Verweise
Pubmed ID: 30444027,30456859
Omia ID: 245